How do multiple dose rodenticides differ from single dose rodenticides in terms of safety?

Multiple dose rodenticides are generally considered safer compared to single dose rodenticides primarily due to their toxicity profile and the way they function. Unlike single dose rodenticides, which are designed to deliver a lethal dose to rodents after one feeding, multiple dose rodenticides require several feedings over a period of time to reach a toxic level. This means that if a non-target animal or human accidentally ingests a small quantity of a multiple dose rodenticide, the amount ingested is less likely to lead to immediate toxicity or death. Furthermore, because of the cumulative nature of multiple dose rodenticides, there is an opportunity for intervention, such as inducing vomiting or administering activated charcoal, which could significantly reduce the risk of a fatal outcome.

This safety aspect makes multiple dose rodenticides more favorable in environments where pets, wildlife, or children may be present, as the risk of acute poisoning is lower. In contrast, single dose formulations can pose a higher risk of rapid lethality, making them more hazardous in such situations.