What are first-generation anticoagulant rodenticides generally regarded as, in comparison to second-generation anticoagulants?

First-generation anticoagulant rodenticides are generally regarded as much safer compared to second-generation anticoagulants. This distinction arises because first-generation anticoagulants typically require multiple feedings for an effective dosage, thus reducing the likelihood of secondary poisoning in non-target species. Their toxicity is generally lower, which makes them a preferable option in environments where the risk of collateral damage to wildlife and pets needs to be minimized.

In contrast, second-generation anticoagulants are more potent and can achieve effective dosages in a single feeding, which increases their efficiency in rodent control. However, this also raises the risk of secondary poisoning to other animals that may consume the poisoned rodents. Therefore, while second-generation products can be more effective in controlling rodent populations, they carry greater risks to non-target species, making first-generation anticoagulants the safer choice in many situations.